Philadelphia Lipid and Atherosclerosis Club (PLAC) & The Cardiovascular Institute of Philadelphia (CVI) proudly present “Gene Editing to Treat Hyperlipidemia
And to Prevent Coronary Heart Disease”

People naturally born with beneficial DNA variants that turn off cholesterol and triglyceride genes like PCSK9 and ANGPTL3 enjoy substantially lower lifetime risk of coronary heart disease, without any serious adverse consequences. Gene editing makes it possible to introduce similar beneficial DNA variants in adult patients–a potential one-shot therapy to permanently reduce cholesterol or triglyceride levels and confer lifelong protection against coronary heart disease.

Dean G. Karalis, MD FACC FNLA
Clinical Professor of Medicine
Sidney Kimmel School of Medicine at
Thomas Jefferson University

Daniel J. Rader MD
Seymour Gray Professor of Molecular Medicine
Perelman School of Medicine at
The University of Pennsylvania

Daniel Soffer, MD FNLA FACP
Clinical Associate Professor of Medicine
Perelman School of Medicine at
The University of Pennsylvania

Kiran Musunuru, MD PhD MPH ML
Professor of Medicine
Perelman School of Medicine at the University of Pennsylvania


August 4, 2020
6:00 PM Eastern

This PLAC/CVI Webinar is FREE to attend and DOES NOT offer CME/CEU Credits.

You MUST Register Online to attend.

  • You will receive a confirmation email from Zoom with a unique link for you to access the online meeting.
  • Do not share the link as it will lock others out trying to use the sign-in link after it has been used.
  • Others who are interested can also register themselves.

Space is Limited- Registration is Required
Admission to the Webinar cannot be provided for those who do not register in advance.

Register Online
Program Brochure


Kiran Musunuru, MD, PhD
Kiran Musunuru, MD, PhDUniversity of Pennsylvania
Dean G. Karalis, MD
Dean G. Karalis, MDThomas Jefferson University
Daniel J. Rader, MD
Daniel J. Rader, MDUniversity of Pennsylvania
Daniel E. Soffer, MD
Daniel E. Soffer, MDUniversity of Pennsylvania